{"created":"2023-05-15T11:01:40.110106+00:00","id":615,"links":{},"metadata":{"_buckets":{"deposit":"ace84dc8-7774-49fe-97ab-e18f1523fb80"},"_deposit":{"created_by":2,"id":"615","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"615"},"status":"published"},"_oai":{"id":"oai:nagaokaut.repo.nii.ac.jp:00000615","sets":["5:16:39:57"]},"author_link":["2719","2718","2726","2717","2722","2729","2730","2721","2725","2732","2733","2723","2728","2727","2716","2731","2720","2724"],"item_4_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Analysis of parkinsonian tremor for biofeedback therapy"}]},"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-12","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"124","bibliographicPageStart":"119","bibliographicVolumeNumber":"18","bibliographic_titles":[{"bibliographic_title":"長岡技術科学大学研究報告"}]}]},"item_4_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The 3 major symptoms of Parkinsonian disease are tremor, akinesia and rigidity. These symptoms are caused by depletion of dopamine in the substantia nigra striatum system. The L－dopa and acetylcholine have been adopted to the standard treatment for Parkinsonian disease. But the applications of these drugs tend to yield undesirable side effects. We propose the biofeedback system for the treatment of tremor. As the biofeedback parameters, we investigated tremor frequency, dopamine level and the Yahr grade. We have found the clear relationship between tremor frequency and dopamine level. Tremor was measured by a accelerometer fixed on the bony part of patients thumb. After the measurement, blood was collected for dopamine analysis. Dopamine was separated with centrifugation, filtration and reverse phase HPLC. The absorbance was monitored at a wavelength of 283nm. As a result, we found a negative relationship between physiological tremor frequency and dopamine level. The correlation coefficient was 0.944. This result suggests that the dopamine level in parkinsonian patients can be estimated by measuring the physiological tremor frequency.","subitem_description_type":"Abstract"}]},"item_4_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"2722","nameIdentifierScheme":"WEKO"}],"names":[{"name":"マツモト, ヨシノブ"}]},{"nameIdentifiers":[{"nameIdentifier":"2723","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ゴンダイラ, ユキヨ"}]},{"nameIdentifiers":[{"nameIdentifier":"2724","nameIdentifierScheme":"WEKO"}],"names":[{"name":"サカキバラ, マサシ"}]},{"nameIdentifiers":[{"nameIdentifier":"2725","nameIdentifierScheme":"WEKO"}],"names":[{"name":"シンドウ, クニハル"}]},{"nameIdentifiers":[{"nameIdentifier":"2726","nameIdentifierScheme":"WEKO"}],"names":[{"name":"タムラ, マサト"}]},{"nameIdentifiers":[{"nameIdentifier":"2727","nameIdentifierScheme":"WEKO"}],"names":[{"name":"フクモト, イチロウ"}]},{"nameIdentifiers":[{"nameIdentifier":"2728","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Matsumoto, Yoshinobu"}]},{"nameIdentifiers":[{"nameIdentifier":"2729","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Gondaira, Yukiyo"}]},{"nameIdentifiers":[{"nameIdentifier":"2730","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sakakibara, Masashi"}]},{"nameIdentifiers":[{"nameIdentifier":"2731","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Shindo, Kuniharu"}]},{"nameIdentifiers":[{"nameIdentifier":"2732","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tamura, Masato"}]},{"nameIdentifiers":[{"nameIdentifier":"2733","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Fukumoto, Ichiro"}]}]},"item_4_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"長岡技術科学大学"}]},"item_4_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00177120","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0388-5631","subitem_source_identifier_type":"ISSN"}]},"item_4_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"長岡技術科学大学RIセンター"},{"subitem_text_value":"長岡技術科学大学生物系"},{"subitem_text_value":"長岡技術科学大学生物系"},{"subitem_text_value":"長岡技術科学大学生物系"},{"subitem_text_value":"長岡西病院神経内科"},{"subitem_text_value":"長岡技術科学大学生物系"}]},"item_4_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松本, 義伸"}],"nameIdentifiers":[{"nameIdentifier":"2716","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"権平, 幸代"}],"nameIdentifiers":[{"nameIdentifier":"2717","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"榊原, 将司"}],"nameIdentifiers":[{"nameIdentifier":"2718","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"新藤, 邦元"}],"nameIdentifiers":[{"nameIdentifier":"2719","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田村, 正人"}],"nameIdentifiers":[{"nameIdentifier":"2720","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福本, 一朗"}],"nameIdentifiers":[{"nameIdentifier":"2721","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-03"}],"displaytype":"detail","filename":"K18_18.pdf","filesize":[{"value":"576.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"K18_18.pdf","url":"https://nagaokaut.repo.nii.ac.jp/record/615/files/K18_18.pdf"},"version_id":"394a9a8e-d79a-49e9-8552-9e3ef8e430a1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Parkinson disease","subitem_subject_scheme":"Other"},{"subitem_subject":"Tremor frequency","subitem_subject_scheme":"Other"},{"subitem_subject":"Dopamine level","subitem_subject_scheme":"Other"},{"subitem_subject":"Yahr grade","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"バイオフィードバック治療を目的としたパーキンソン病患者の振戦周波数解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"バイオフィードバック治療を目的としたパーキンソン病患者の振戦周波数解析"}]},"item_type_id":"4","owner":"2","path":["57"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-02-15"},"publish_date":"2011-02-15","publish_status":"0","recid":"615","relation_version_is_last":true,"title":["バイオフィードバック治療を目的としたパーキンソン病患者の振戦周波数解析"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-15T18:50:19.159372+00:00"}